Bruno Geloneze Neto

Faculdade de Ciências Médicas – Universidade Estadual de Campinas

 Laboratório de Investigação em Diabetes e Metabolismo – LIMED

O LIMED é um dos principais centros de pesquisa na fisiopatologia e epidemiologia do diabetes e da obesidade do Brasil.

EQUIPE

PÓS-Doutorado

• Marcelo Miranda de Oliveira Lima
• Marina Norde

Doutorado

• Maria Eduarda Martelli
• Isabela Solar

Mestrado

• Gabrielli Gabatini
• Jorge Violante Cumpa
• Vinícius Ferreira dos Santos
• Caroline Almiro

Iniciação Científica

• Laura Ramos Gonçalves

BOLSISTA SAE (SERVIÇO DE APOIO AO ESTUDANTE)

• Gislaine Pereira Lopes

PRINCIPAIS DESCOBERTAS

• Caracterização de propriedades nutracêuticas de produtos derivados de plantas nacionais.
• Descoberta de marcadores substitutivos laboratoriais e antropométricos de resistência à insulina através do estudo: Brazilian Metabolic Syndrome Study (BRAMS)
• Cooperação internacional para elaboração de recomendações para o manejo da obesidade e do diabetes em tempos da pandemia pelo COVID-19.
• Participação no estudo Nutritionists Health Study (NutriHS)

PRINCIPAIS ARTIGOS 

1. Association of physical activity and sitting with metabolic syndrome and hyperglycemic clamp parameters in adolescents–BRAMS pediatric study. Talita Oliveira Silva, Marina Maintinguer Norde, Ana Carolina Vasques, Mariana Porto Zambom, Maria Angela Reis de Góes Antonio, Ana Maria De Bernardi Rodrigues, Bruno Geloneze, Brazilian Metabolic Syndrome Study investigators. Frontiers in Endocrinology 1191935 Volume 14

2. Metformin acts in the gut and induces gut-liver crosstalk. Tobar N, Rocha GZ, Santos A, Guadagnini D, Assalin HB, Camargo JA, Gonçalves AESS, Pallis FR, Oliveira AG, Rocco SA, Neto RM, de Sousa IL, Alborghetti MR, Sforça ML, Rodrigues PB, Ludwig RG, Vanzela EC, Brunetto SQ, Boer PA, Gontijo JAR, Geloneze B, Carvalho CRO, Prada PO, Folli F, Curi R, Mori MA, Vinolo MAR, Ramos CD, Franchini KG, Tormena CF, Saad MJA. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2211933120. doi: 10.1073/pnas.2211933120. Epub 2023 Jan 19.

3.Gestational weight gain and visceral adiposity in adult offspring: Is there a link with the fecal abundance of Acidaminococcus genus? Freitas RGBON, Vasques ACJ, Fernandes GR, Ribeiro FB, Solar I, Barbosa MG, Almeida-Pititto B, Geloneze B, Ferreira SRG. Eur J Clin Nutr. 2022 Dec;76(12):1705-1712. doi: 10.1038/s41430-022-01182-7.

4. Associations of Blautia Genus With Early-Life Events and Later Phenotype in the NutriHS. Freitas RGBON, Vasques ACJ, Fernandes GDR, Ribeiro FB, Solar I, Barbosa MG, Pititto BA, Geloneze B, Ferreira SRG. Front Cell Infect Microbiol. 2022 May 12;12:838750.

5. Jabuticaba juice improves postprandial glucagon-like peptide-1 and antioxidant status in healthy adults: a randomized crossover trial. Geraldi MV, Cazarin CBB, Cristianini M, Vasques AC, Geloneze B, Maróstica Júnior MR. Br J Nutr. 2021 Nov 15:1-29. doi: 10.1017/S0007114521004530.

6. COVID-19 and metabolic disease: mechanisms and clinical management. Steenblock C, Schwarz PEH, Ludwig B, Linkermann A, Zimmet P, Kulebyakin K, Tkachuk VA, Markov AG, Lehnert H, de Angelis MH, Rietzsch H, Rodionov RN, Khunti K, Hopkins D, Birkenfeld AL, Boehm B, Holt RIG, Skyler JS, DeVries JH, Renard E, Eckel RH, Alberti KGMM, Geloneze B, Chan JC, Mbanya JC, Onyegbutulem HC, Ramachandran A, Basit A, Hassanein M, Bewick G, Spinas GA, Beuschlein F, Landgraf R, Rubino F, Mingrone G, Bornstein SR. Lancet Diabetes Endocrinol. 2021 Nov;9(11):786-798. doi: 10.1016/S2213-8587(21)00244-8.

7. Consequences of the COVID-19 pandemic for patients with metabolic diseases. Bornstein SR, Rubino F, Ludwig B, Rietzsch H, Schwarz PEH, Rodionov RN, Khunti K, Hopkins D, Birkenfeld AL, Boehm B, Amiel S, Holt RIG, Skyler JS, DeVries JH, Renard E, Eckel RH, Zimmet P, Alberti KG, Geloneze B, Chan JC, Mbanya JC, Onyegbutulem HC, Ramachandran A, Basit A, Hassanein M, Spinas GA, Beuschlein F, Mingrone G. Nat Metab. 2021 Mar;3(3):289-292.

8. Insulin Resistance in Congenital Adrenal Hyperplasia is Compensated for by Reduced Insulin Clearance. de Oliveira DM, Tura A, Vasques ACJ, Camilo DF, Lima MM, de Lemos-Marini SHV, Goncalves EM, Guerra-Junior G, Geloneze B. J Clin Endocrinol Metab. 2021 Mar 25;106(4):e1574-e1585.

9. Practical recommendations for the management of diabetes in patients with COVID-19. Bornstein SR, Rubino F, Khunti K, Mingrone G, Hopkins D, Birkenfeld AL, Boehm B, Amiel S, Holt RI, Skyler JS, DeVries JH, Renard E, Eckel RH, Zimmet P, Alberti KG, Vidal J, Geloneze B, Chan JC, Ji L, Ludwig B. Lancet Diabetes Endocrinol. 2020 Jun;8(6):546-550.

10. Insulin does not stimulate β-alanine transport into human skeletal muscle.  Gonçalves LS, Kratz C, Santos L, Carvalho VH, Sales LP, Nemezio K, Longobardi I, Riani LA, Lima MMO, Saito T, Fernandes AL, Rodrigues J, James RM, Sale C, Gualano B, Geloneze B, de Medeiros MHG, Artioli GG. Am J Physiol Cell Physiol. 2020 Apr 1;318(4):C777-C786.